Sleep & Recovery
Peptides researched for sleep quality improvement, circadian rhythm support, and nighttime recovery optimization. Each compound links to its full dosing protocol.
Research Use Only. All dosing information is for educational purposes. Consult a licensed healthcare provider before making health decisions.
DSIP
Delta Sleep-Inducing Peptide that promotes deep slow-wave (delta) sleep. Researched for normalizing sleep architecture, reducing sleep latency, and improving overall sleep quality.
Route: Subcutaneous injection
Reconstitution: 3.0 mL bacteriostatic water → ~1.67 mg/mL concentration
Dose Range: 100–300 mcg once daily (gradual titration); advanced up to 500 mcg
Cycle: 4–8 weeks; optional extension to 12 weeks with periodic breaks
Schedule: Week 1: 100 mcg 6 → Week 2: 150 mcg 9 → Week 3: 200 mcg 12 → Weeks 4–8: 250–300 mcg 15–18
- The influence of synthetic DSIP (delta-sleep-inducing-peptide) on disturbed human sleep — Experientia, 1981
- Effects of delta sleep-inducing peptide on sleep of chronic insomniac patients. A double-blind study — Neuropsychobiology, 1992
- Phosphorylated delta sleep inducing peptide restores spatial memory and p-CREB expression by improving sleep architecture at high altitude — Life Sci, 2018
Selank
Anxiolytic peptide that reduces stress and anxiety, common barriers to quality sleep. By modulating GABA and serotonin pathways, it supports relaxation and sleep onset.
Route: Subcutaneous injection
Reconstitution: 3.0 mL bacteriostatic water → ~1.67 mg/mL concentration
Dose Range: 300–500 mcg once daily subcutaneously (gradual titration)
Schedule: Weeks 1–2: 300 mcg 18 → Weeks 3–4: 500 mcg 30 → Weeks 1–2: 300 mcg 9 → Weeks 3–4: 500 mcg 15
- GABA and glutamate in the human brain — Neuroscientist, 2002
- GABA and l-theanine mixture decreases sleep latency and improves NREM sleep — Pharm Biol, 2019
- Current status of GABA receptor subtypes in analgesia — Biomed Pharmacother, 2023
Ipamorelin
Growth hormone secretagogue that amplifies the natural GH pulse during deep sleep. Supports overnight tissue repair, recovery, and body composition improvement.
Route: Subcutaneous injection
Reconstitution: 3.0 mL bacteriostatic water → ~1.67 mg/mL concentration
Dose Range: 100–250 mcg once daily (gradual titration recommended)
Cycle: 8–12 weeks; optional extension to 16 weeks, followed by 2–4 week off-cycle
Schedule: Weeks 1–2: 100 mcg 6 → Weeks 3–4: 150 mcg 9 → Weeks 5–8: 200 mcg 12 → Weeks 9–12: 250 mcg 15
- Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions — J Am Acad Orthop Surg Glob Res Rev, 2026
- Sleep Consequences of Prader-Willi Syndrome — Curr Neurol Neurosci Rep, 2023
- Altered nocturnal growth hormone (GH) secretion in obsessive compulsive disorder — Psychoneuroendocrinology, 2006
CJC No DAC
GHRH analog often paired with ipamorelin for pre-sleep dosing. Amplifies natural growth hormone release during sleep cycles for enhanced overnight recovery.
Route: Subcutaneous injection
Reconstitution: 3.0 mL bacteriostatic water → ~1.67 mg/mL concentration
Dose Range: 100–300 mcg once daily (gradual titration)
Cycle: 8–12 weeks; optional extension to 16 weeks
Schedule: Weeks 1–2: 100 mcg 6 → Weeks 3–4: 150 mcg 9 → Weeks 5–6: 200 mcg 12 → Weeks 7–12: 250–300 mcg 15–18
- Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults — J Clin Endocrinol Metab, 2006
- Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions — J Am Acad Orthop Surg Glob Res Rev, 2026
- Injectable Peptide Therapy: A Primer for Orthopaedic and Sports Medicine Physicians — Am J Sports Med, 2026
Pinealon
Tripeptide that supports pineal gland function and melatonin regulation. Researched for normalizing circadian rhythms and supporting healthy sleep patterns, particularly in aging.
Route: Subcutaneous injection or Oral
Reconstitution: 3.0 mL bacteriostatic water → ~6.67 mg/mL concentration
Dose Range: 1.0–2.0 mg once daily for 10–20 day cycles
Cycle: Standard 10–20 days; repeat cycles every 2–3 months
- Sleep physiology, pathophysiology, and sleep hygiene — Prog Cardiovasc Dis, 2023
- About sleep’s role in memory — Physiol Rev, 2013
- Sleep and human cognitive development — Sleep Med Rev, 2021
All information is intended strictly for educational and research purposes. Not medical advice. Consult a licensed healthcare provider before making any health decisions.