Prostamax

Prostamax (Oral)

Prostamax is described in the peptide bioregulator space as a prostate-directed peptide complex derived from prostate tissue peptides. It is investigated for potential support of prostate tissue homeostasis, inflammatory balance, and age‑related prostate changes. Robust peer‑reviewed Western clinical data are limited.

Dosing Protocols

Reconstitute: Add 2.0 mL bacteriostatic water → 10 mg/mL concentration.
Typical daily range: 500 mcg–1 mg once daily (gradual titration).
Easy measuring: At 10 mg/mL, 1 unit = 0.01 mL = 100 mcg (0.1 mg) on a U-100 insulin syringe.
Storage: Lyophilized: refrigerate at 4 °C short-term or freeze at −20 °C long-term; reconstituted: refrigerate at 2–8 °C, use within 2 weeks.

Schedule: Daily intramuscular injections for 8–12 weeks (extend to 16 weeks if desired).
Cycle Length: 8–12 weeks; optional extension to 16 weeks.
Goal: Support prostate tissue health and function through bioregulatory peptide signaling.

Frequency: Inject once daily intramuscularly.

Phase	Dose	Syringe (U-100)
Weeks 1–2	500 mcg (0.5 mg)	5 units (0.05 mL)
Weeks 3–4	750 mcg (0.75 mg)	7.5 units (0.075 mL)
Weeks 5–8	1,000 mcg (1 mg)	10 units (0.10 mL)
Weeks 9–12	1,000 mcg (1 mg)	10 units (0.10 mL)

Benefits

• Studied for support of prostate tissue homeostasis in aging models
• May help normalize inflammatory signaling in prostate tissue (preclinical/observational)
• Investigated for support of lower urinary tract symptom resilience (limited evidence)
• Potential support for prostate microcirculation and trophic signaling (hypothesized)
• Explored as adjunct support after prostatitis-like inflammatory stress (limited evidence)
• May support cellular repair processes under oxidative stress (preclinical)

Mechanism of Action

Bioregulator peptides are proposed to deliver short organ-specific signaling sequences that modulate gene expression and protein synthesis in target tissue. For prostate-directed complexes, hypothesized effects include normalization of androgen-responsive gene expression balance, modulation of local cytokines, and regulation of apoptosis/proliferation equilibrium. Specific molecular targets are not well characterized publicly.

Side Effects

• GI upset
• Headache
• Sleep changes
• Allergic reaction (rare)

Side Effect Management

• Take with meals if GI upset
• Start with half-dose for 3–5 days
• Stop if rash/swelling occurs

Contraindications

• Known/suspected prostate cancer without medical supervision (symptom masking risk)
• Pregnancy/breastfeeding
• Known peptide hypersensitivity
• Severe hepatic/renal impairment (precaution)

Research Citations

PubMed/DOI-linked citations for verification. Many studies are preclinical (animal/in-vitro) or early clinical.

1. Khavinson V, Linkova N. Peptides: Prospects for use in aging and age-related diseases (bioregulators). DOI Link
2. Ashmarin IP, Khavinson V. Regulatory peptides: mechanisms and applications. (review). DOI Link
3. Khavinson VKh. Peptide regulation of gene expression (review). DOI Link

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