Anti-Aging
Peptides researched for telomere support, mitochondrial function, skin quality, and longevity pathways. Each compound links to its full dosing protocol.
Research Use Only. All dosing information is for educational purposes. Consult a licensed healthcare provider before making health decisions.
Epithalon
Synthetic tetrapeptide that activates telomerase, potentially elongating telomeres. Researched for pineal gland function, melatonin regulation, and anti-aging effects at the cellular level.
Route: Subcutaneous injection
Reconstitution: 2.0 mL bacteriostatic water → 5 mg/mL concentration
- Telomere and telomerase biology — Prog Mol Biol Transl Sci, 2014
- Genetics of human telomere biology disorders — Nat Rev Genet, 2023
- Telomeres and telomerase: three decades of progress — Nat Rev Genet, 2019
GHK-Cu
Copper peptide that resets gene expression toward a healthier state. Stimulates collagen synthesis, reduces inflammation, and supports tissue remodeling and skin rejuvenation.
Route: Subcutaneous injection
Reconstitution: 3.0 mL sterile water → 16.67 mg/mL concentration
Dose Range: 1–2 mg once daily (gradual titration over 12 weeks)
Cycle: 8–12 weeks typical; may extend to 16 weeks
- The Cutaneous Telocytes — Adv Exp Med Biol, 2016
- A comparative study of the effects of retinol and retinoic acid on histological, molecular, and clinical properties of human skin — J Cosmet Dermatol, 2016
- Basement membranes and autoimmune diseases — Matrix Biol, 2017
NAD+
Essential coenzyme for cellular energy metabolism and sirtuin activation. Declines with age; supplementation researched for DNA repair, mitochondrial function, and healthspan extension.
Route: Oral
Reconstitution: 3.0 mL bacteriostatic water → 166.7 mg/mL concentration
Dose Range: 50–100 mg once daily subcutaneously (gradual titration from lower doses)
Schedule: Week 1: 50 mg 30 → Week 2: 75 mg 45 → Weeks 3–16: 100 mg 60 → Week 1: 50 mg 15
- NAD⁺ in aging, metabolism, and neurodegeneration — Science, 2015
- NAD+ and sirtuins in aging and disease — Trends Cell Biol, 2014
- NAD(+) homeostasis in health and disease — Nat Metab, 2020
SS-31 (Elamipretide)
Mitochondria-targeted peptide that stabilizes cardiolipin in the inner mitochondrial membrane. Researched for protecting against age-related mitochondrial dysfunction and oxidative damage.
Route: Subcutaneous injection
Reconstitution: 1.0 mL bacteriostatic water → 10 mg/mL concentration
Dose Range: 5–10 mg once daily (gradual titration); advanced protocols may reach 15–20 mg/day under supervision
Cycle: 8–12 weeks; limited data exists beyond 12 weeks
Schedule: Weeks 1–2: 5 mg → Weeks 3–8: 10 mg → Weeks 5–8: 15 mg Split: → Weeks 9–12: 20 mg Split:
- Elamipretide: A Review of Its Structure, Mechanism of Action, and Therapeutic Potential — Int J Mol Sci, 2025
- ALCAT1-mediated abnormal cardiolipin remodelling promotes mitochondrial injury in podocytes in diabetic kidney disease — Cell Commun Signal, 2024
- Aging, mitochondrial dysfunction, and cerebral microhemorrhages: a preclinical evaluation of SS-31 (elamipretide) and development of a high-throughput machine learning-driven imaging pipeline for cerebromicrovascular protection therapeutic screening — Geroscience, 2025
Thymosin Alpha-1
Immune-modulating peptide that supports thymic function, which naturally declines with age. Researched for immune rejuvenation and enhanced host defense in aging populations.
Route: Subcutaneous injection
Reconstitution: 3.0 mL bacteriostatic water → ~1.67 mg/mL concentration
Dose Range: 300–500 mcg once daily (gradual titration)
Cycle: 8–12 weeks; optional extension to 16 weeks
Schedule: Week 1: 300 mcg → Weeks 2–8: 500 mcg → Week 1: 300 mcg → Weeks 2–8: 500 mcg
- Immunosenescence and inflammaging in the aging process: age-related diseases or longevity? — Ageing Res Rev, 2021
- An aged immune system drives senescence and ageing of solid organs — Nature, 2021
- B Cell Immunosenescence — Annu Rev Cell Dev Biol, 2020
MOTS-C
Mitochondrial-derived peptide that regulates metabolic homeostasis. Researched for exercise mimetic effects, insulin sensitivity, and protection against age-related metabolic decline.
Route: Subcutaneous injection
Reconstitution: 3.0 mL bacteriostatic water → ~1.67 mg/mL concentration
Dose Range: 500–1500 mcg once daily (gradual titration from 500 mcg)
Cycle: 4–8 weeks on, followed by 4–8 weeks off; avoid continuous long-term use without breaks
Schedule: Weeks 1–2: 500 mcg → Weeks 3–4: 1000 mcg → Weeks 5–6: 1500 mcg → Weeks 7–8: 2000 mcg
- Systematic profiling reveals betaine as an exercise mimetic for geroprotection — Cell, 2025
- A Synthetic ERR Agonist Alleviates Metabolic Syndrome — J Pharmacol Exp Ther, 2024
- The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance — Cell Metab, 2015
All information is intended strictly for educational and research purposes. Not medical advice. Consult a licensed healthcare provider before making any health decisions.